Effect of Fermented Nunu on Serum Lipid Profile of Female Wistar Rats

Abstract

Several studies have established the relationship between an individual’s lipid profile and risk of  cardiovascular  diseases  which  accounts  for  a  high  mortality  rate  in  women.  This  study delves into the effect of fermented nunu in female Wistar rats while exploring the possibility of reducing  cardiovascular  risks.  Four  different  samples  of  fermented  milk  namely;  yogurt, laboratory fermented milk (nunu), locally fermented milk, and the normal feed and water (as control) was used to feed the female Wistar rats for 14 days after which they were sacrificed. Blood samples were collected and analyzed for HDL, LDL, triglycerides, and total cholesterol. The result of the summation of the mean for the LDL (low-density lipoprotein) analysis are as follows; 56.416(group 1), 52.785(group 2), 48.479(group 3), and 53.810mg/dl (group 4). The result for the summation of the mean for the total cholesterol is as follows 80.892(group 1),78.411(group 2), 82.891(group 3), 76.764mg/dl (group 4). The result of the summation of the mean   for   the   triglycerides   analysis   is   as   follows   57.42(group   1),   55.425(group   2),60.197(group 3), 56.654mg/dl (group 4). The result of the summation of the mean for the HDL (high-density   lipoprotein)   analysis   is   as   follows   51.267(group   1),   53.385(group   2),46.073(group 3), 52.269 mg/dl (group 4).The effect of fermented nunu on the total cholesterol, triglycerides, HDL, and LDL was more remarkable in rat subjects fed Yoghurt and Laboratory Fermented Nunu.